Clinical observation on effect of Kanglaite Injection combined with chemoembolization in treating primary middle and late stage liver cancer

[Abstract] Objective: To evaluate efficacy of Kanglaite Injection (KLT) combined with chemoembolization in treating primary middle and late stage liver cancer. Methods: 80 patients were randomly divided into two groups. 40 patients in treatment group were treated with Kanglaite Injection combined with chemoembolization. The other 40 patients in control group received chemoembolization alone. Change of clinical symptom, Karnofsky status, blood biochemical indexes, and short term effect were observed and clinical data were processed. Results: Treatment group was significantly superior to control group in improving clinical symptoms, controlling tumor growth, gaining body weight, increasing KPS and relieving side reaction of chemotherapy in bone marrow toxicity (leukopenia and thrombocytopenia), P<0.05. However in hypochromasia, liver function damage, nausea and vomiting, there was no significant difference between the two groups (P>0.05). Conclusion: Kanglaite Injection had remarkable effect in improving survival quality, relieving toxic side reaction after chemoembolization. Its efficacy was confirmed and KLT is worth to be recommended.