Optimal path to epigenetic switching.
نویسندگان
چکیده
We use large deviation methods to calculate rates of noise-induced transitions between states in multistable genetic networks. We analyze a synthetic biochemical circuit, the toggle switch, and compare the results to those obtained from a numerical solution of the master equation.
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عنوان ژورنال:
- Physical review. E, Statistical, nonlinear, and soft matter physics
دوره 71 1 Pt 1 شماره
صفحات -
تاریخ انتشار 2005