Studies on Different Classes of Mutations Induced by Radiation of Drosophila Melanogaster Females.
نویسندگان
چکیده
ELETERIOUS mutations are produced in the germ plasm when animals are exposed to total body radiation. The ovaries of most higher animals contain germ cells a t different stages of development, and these cells may be expected to be affected to different degrees by ionizing radiation. I t is, therefore, of both practical and theoretical interest to study the mutation frequency in successive batches of germ cells produced by females subsequent to radiation exposure, since it is important to know whether or not mutated cells are eliminated from the germ line and if mutant-free eggs are eventually produced.
منابع مشابه
Aconitase and Developmental EndPointsasEarly IndicatorsofCellularToxicity Induced by Xenobiotics in Drosophila Melanogaster
Background: In this study, the toxicity of the different xenobiotics was tested on the fruit fly Drosophila melanogaster model system. Methods: Fly larvae were raised on food supplemented with xenobioticsat different concentrations (sodium nitroprusside (0.1-1.5 mM), S-nitrosoglutathione (0.5-4 mM), and potassium ferrocyanide (1 mM)). Emergence of flies, food intake by larvae, and pupation h...
متن کاملConcentration dependent effect of morphine, aspirin, capsaicin and chili pepper hydro alcoholic extract on thermal and chemical pain model in fruit fly (Drosophila melanogaster)
Introduction: Pain research using animal models is related to ethical concerns, so invertebrates and insects have been recommended by researchers. In the present study, the nociceptive and antinociceptive effects of capsaicin, aspirin, morphine and chili extract were examined using fruit fly (Drosophila melanogaster) as an alternative for rodent pain model. Methods: Stage 3 of larvae and ad...
متن کاملToxicological Evaluation of a New Lepidopteran Insecticide, Flubendiamide, in Non-Target Drosophila melanogaster Meigen (Diptera: Drosophilidae)
Background: Flubendiamide, comparatively a new pesticide designed to eradicate lepidopteran insect pests is known to have low risk to birds, mammals, fish, algae, honey bees, non-target arthropods, earthworms, soil macro- and micro-organisms, non-target plants as well as sewage treatment organisms; however, the risk assessment for aquatic invertebrates from metabolite could not be finalized wit...
متن کاملThe intercellular distribution of mutations induced in oocytes of Drosophila melanogaster by chemical and physical mutagens.
When females of Drosophila melanogaster are treated with chemical or physical mutagens, not only in one but also in both of the two homologous X chromosomes of a given oocyte, a recessive sex-linked lethal mutation may be induced. A method is described that discriminates between such "single" and "double mutations". A theory is developed to show how a comparison between the expected and the obs...
متن کاملPotent mutagenicity of urethan (ethyl carbamate) gas in Drosophila melanogaster.
Exposure of spermatozoa to urethan (ethyl carbamate) gas induced a high frequency of X-linked recessive lethal mutations detected by the Muller-5 technique in Drosophila melanogaster. and a clear dose response was observed. Mutagenic activity of urethan gas on mature spermatozoa following 1.5 (2.4% mutations per chromosome) and 5.5 hr (5.5%) exposure is approximately equal to that induced by 10...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Genetics
دوره 41 6 شماره
صفحات -
تاریخ انتشار 1956