Pomeranz/ pp22-25
نویسنده
چکیده
Imaging biomarkers are accepted surrogate endpoints for several therapeutic indications in clinical research and are increasingly forming the basis for regulatory approval. The appropriate clinical trial design and imaging acquisition protocol ensures the accuracy, quality and consistency of imaging data submitted to regulatory agencies. Two of the most widely used medical imaging technologies are computed tomography (CT) and magnetic resonance imaging (MRI). Both modalities can be used for a variety of indications, therapeutic areas and disease states in biopharmaceutical and medical device trials, and each has unique benefits. When developing a clinical trial and imaging acquisition protocol, the differences between all available imaging modalities must be considered. In the case of CT and MRI, the differences can be synthesised into three primary categories: scanner technology, appropriateness to anatomical region and safety considerations.
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تاریخ انتشار 2007