Genotypic characterization of HIV-1 C variants in PBMCs and cervicovaginal cells

نویسندگان

  • Varsha M Prabhu
  • Varsha S Padwal
  • Shilpa M Velha
  • Atmaram H Bandivdekar
چکیده

Background HIV-1 is primarily a mucosal pathogen since more than 80% of infections occur through genital exposure. Vaginal intercourse, though an inefficient mode of transmission, contributes more new infections worldwide than any other route. Also, the female reproductive tract has been identified as a compartment that harbors variants distinct from blood. Present study aims to highlight viral compartmentalization between these compartments reflecting inadequate ART penetration.

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عنوان ژورنال:

دوره 14  شماره 

صفحات  -

تاریخ انتشار 2014