Causation, bias and confounding: a hitchhiker's guide to the epidemiological galaxy. Part 1. Principles of causality in epidemiological research: time order, specification of the study base and specificity.

نویسنده

  • Samuel Shapiro
چکیده

©FSRH J Fam Plann Reprod Health Care 2008: 34(2) Definitions and methods In this series of articles the focus is on epidemiology as a tool in the exploration of causation. Other functions (e.g. administrative functions such as monitoring birth or death rates, or life expectancy, or the use of epidemiological data for guidance in health policy) are not considered. In epidemiological research possible causation (or prevention) is explored by determining and comparing the incidence (‘occurrence’) of diseases (‘outcomes’, ‘events’), as these occur among exposed and non-exposed persons in defined populations, over specified time intervals. Incidence per unit time is known as an incidence rate. A defined or implied population/time experience is known as a study base, and it can be analysed in two ways: in a follow-up (‘cohort’) study or in a case-control (‘casereferent’) study.

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عنوان ژورنال:
  • The journal of family planning and reproductive health care

دوره 34 2  شماره 

صفحات  -

تاریخ انتشار 2008