Light Diffraction by Single Striated Muscle Fibers

LIGHT DIFFRACTION BY SINGLE STRIATED MUSCLE FIBERSf

2. Morphological Approach to the Neurotransmission System

At present a number of neuromodulators are found and their localization in the nervous system has been examined by using immunocytochemical technique. One of the most interesting topics in this field is a problem of the colocalization of multiple neuromodulators in single neurons. For example, calcitonin gene-related peptide (CGRP) coexists with acetylcholine (Ach) in single motor neurons inner...

Monitoring sarcomere structure changes in whole muscle using diffuse light reflectance.

Normal biomechanical and physiological functions of striated muscles are facilitated by the repeating sarcomere units. Light scattering technique has been used in studying single extracted muscle fibers. However, few studies, if any, have been conducted to investigate the possibility of using optical detection to examine sarcomere structure changes in whole muscles. We conducted a series of exp...

The filament lattice of striated muscle.

The filament lattice of striated muscle is an overlapping hexagonal array of thick and thin filaments within which muscle contraction takes place. Its structure can be studied by electron microscopy or X-ray diffraction. With the latter technique, structural changes can be monitored during contraction and other physiological conditions. The lattice of intact muscle fibers can change size throug...

Coupled expression of troponin T and troponin I isoforms in single skeletal muscle fibers correlates with contractility.

Striated muscle contraction is powered by actin-activated myosin ATPase. This process is regulated by Ca(2+) via the troponin complex. Slow- and fast-twitch fibers of vertebrate skeletal muscle express type I and type II myosin, respectively, and these myosin isoenzymes confer different ATPase activities, contractile velocities, and force. Skeletal muscle troponin has also diverged into fast an...