Molecular Biology of Thermoregulation Invited Review: Effects of heat and cold stress on mammalian gene expression
نویسندگان
چکیده
LARRY A. SONNA,1 JUN FUJITA,2 STEPHEN L. GAFFIN,1 AND CRAIG M. LILLY3 1Thermal and Mountain Medicine Division, United States Army Research Institute of Environmental Medicine, Natick 01760; 3Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital/Harvard Medical School, Boston, Massachusetts 02115; and 2Department of Clinical Molecular Biology, Faculty of Medicine, Kyoto University, Sakyo-ku, Kyoto 6068507, Japan
منابع مشابه
Molecular biology of thermoregulation.
Our ability to thermoregulate is a key physiological characteristic of humans and all other mammals. Therefore, exploring the physiological mechanisms underlying thermoregulation has been the focus of substantial scientific investigation for a number of years. Studies have ranged from those assessing the ability of humans to tolerate heat and cold stress in occupational, military, and recreatio...
متن کاملInvited review: Effects of heat and cold stress on mammalian gene expression.
This review examines the effects of thermal stress on gene expression, with special emphasis on changes in the expression of genes other than heat shock proteins (HSPs). There are approximately 50 genes not traditionally considered to be HSPs that have been shown, by conventional techniques, to change expression as a result of heat stress, and there are <20 genes (including HSPs) that have been...
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Background and purpose: Colorectal cancer (CRC) is ranked as the second most common cancer in men and the third most common cancer in women worldwide. Routine treatments have many side effects and little efficiency. The aim of this study was to investigate the effects of Cold Atmospheric Plasma (CAP) on epigenetic changes of some genes involved in CRC progression. Materials and methods: Prolif...
متن کاملMolecular Biology of Thermoregulation Invited Review: Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance
Kregel, Kevin C. Invited Review: Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. J Appl Physiol 92: 2177–2186, 2002; 10.1152/japplphysiol.01267.2001.— Cells from virtually all organisms respond to a variety of stresses by the rapid synthesis of a highly conserved set of polypeptides termed heat shock proteins (HSPs). The precise functions o...
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van Breukelen, Frank, and Sandra L. Martin. Invited Review: Molecular adaptations in mammalian hibernators: unique adaptations or generalized responses? J Appl Physiol 92: 2640–2647, 2002; 10.1152/ japplphysiol.01007.2001.—Hibernators are unique among mammals in their ability to attain, withstand, and reverse low body temperatures. Hibernators repeatedly cycle between body temperatures near zer...
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تاریخ انتشار 2002