Prevalence of Hypothyroidism in Prgnancy And Pregnancy Outcome
نویسنده
چکیده
The second most common endocrinological disorder in pregnancy is thyroid dysfunction. The most common cause of hypothyroidism is primary abnormality in thyroid. Thyroid hormone is essential for the normal development of the placenta. There is evidence that preeclampsia, placental abruption and preterm labor are all causatively linked to faulty early placentation. Thyroid hormone is important for normal neuronal migration, synaptic transmission and myelination during the early stages of neurodevelopment and hence healthy development of foetus. Aim Of The Study: To study the prevalence of hypothyroidism in pregnancy and the pregnancy outcome in those pregnancies. This study involves screening 1000 consenting eligible women during first trimester. They will be subjected to TSH screening and if the values are deranged then they will undergo FT4. Based on the reports they will be classified as euthyroid, hypothyroid, subclinical hypothyroid and hyperthyroid. For the purpose of this study the patients who are hypothyroid and subclinical hypothyroid will be followed till the termination of pregnancy. All the patients will be treated based on the thyroid profile. Thyroid profile will be repeated every 4 weeks up to 20 weeks and at 32 weeks of gestation and doses titrated accordingly. The normal patients will serve as controls. In our study, there is an increase in the number of spontaneous abortion, GDM, Pre-eclampsia, oligohydramnios, preterm labor, IUGR and low birth weight in inadequately treated group. Hence early diagnosis and adequate treatment of maternal hypothyroidism in pregnancy is essential in decreasing the incidence of complications like abortion, pre eclampsia, IUGR, placental abruption, oligohydramnios and low birth weight which are associated with hypothyroidism.
منابع مشابه
Prevalence of Hypothyroidism during Pregnancy
Hypothyroidism is a common disorder in women in their reproductive age. The present study shows that the prevalence of hypothyroidism is 9% in pregnant women. The study also reveals that of hypothyroidism are adequately treated and monitored good maternal and fetal outcome results. Evidence from the present study supports the need for screening of hypothyroidism in pregnancy.
متن کاملThe Prevalence of Hypothyroidism Based on Risk Factors in Pregnant Women Referred to Shahid Dadbin Clinic, Kerman, Iran
Background & Aims: Since at early pregnancy (<20 week) fetal thyroid gland is undeveloped, normal development of the Fetal brain is highly dependent on maternal thyroid hormones. There are excessive adverse perinatal outcomes associated with overt and subclinical hypothyroidism such as increase of Abortion, preeclampsia, placenta Abruption, LBW, preterm labor, impaired fetal neuropsychological ...
متن کاملSubclinical hypothyroidism: Identification and treatment in pregnancy
Thyroid disorders are the commonly detected endocrinopathies during pregnancy. It seems that prevalence of hypothyroidism is more in Asian countries compared with the West [1,2]. The majority of cases of hypothyroidism are considered to be subclinical type. In west, the prevalence of hypothyroidism is estimated to be 2-3% and 0.3-0.5% for subclinical and overt hypothyroidism respectively [2-4]....
متن کاملThyroid dysfunction in pregnancy
Maternal thyroid state is an important predictor of pregnancy outcome. Both hyperthyroidism and hypothyroidism have been shown to have an adverse impact on pregnancy. There is a wide range in the prevalence of thyroid dysfunction worldwide. In the USA which is considered an iodine replete country, 2%–3% of apparently healthy, non pregnant women of childbearing age have an elevated serum TSH wit...
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تاریخ انتشار 2017