Author’s response to reviews Title: Nitrous oxide induced subacute combined degeneration with longitudinally extensive myelopathy with inverted V-sign on spinal MRI: a case report and literature review Authors:
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Title: Nitrous oxide induced subacute combined degeneration with longitudinally extensive myelopathy with inverted V-sign on spinal MRI: a case report and literature review Authors: Jun Liang Yuan ([email protected]) Shuang Kun Wang ([email protected]) Tao Jiang ([email protected]) Wenli Hu ([email protected]) Version: 5 Date: 23 Nov 2017 Author’s response to reviews: Response to reviewers Dear Editors,
منابع مشابه
Nitrous oxide induced subacute combined degeneration with longitudinally extensive myelopathy with inverted V-sign on spinal MRI: a case report and literature review
BACKGROUND Nitrous oxide (N2O), a long-standing anesthetic, is also neurotoxic by interfering with the bioavailability of vitamin B12 if abused. A few case studies have reported the neurological and psychiatric complications of N2O. CASE PRESENTATION Here, we reported a patient of N2O induced subacute combined degeneration (SCD) with longitudinally extensive myelopathy with inverted V-sign ex...
متن کاملSubacute combined degeneration caused by nitrous oxide intoxication: case reports.
PURPOSE Case reports with a comprehensive review of the current literature concerning subacute combined degeneration induced by nitrous oxide inhalation. A differential diagnosis should be considered when young patients present with progressive myelopathy because that the misuse of nitrous oxide has potentially serious outcomes. CASES REPORT Three young patients aged from 18 to 24, one male a...
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We describe a case of a young woman who developed myelopathy and peripheral neuropathy following 1 year of recreational nitrous oxide (N2O) use. She presented with uncomfortable tingling sensation in her feet and poor balance. Physical examination revealed mild weakness and hyper-reflexia in the lower limbs. Proprioception and vibration were absent in the lower limbs. Pinprick and light touch s...
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2. Hathout L, El-Saden S. Nitrous oxide-induced B12 deficiency myelopathy: perspectives on the clinical biochemistry of vitamin B12. J Neurol Sci. 2011;301(1-2):1-8. https://doi.org/10.1016/j.jns.2010.10.033 3. Gupta PK, Gupta RK, Garg RK, Rai Y, Roy B, Pandey CM et al. DTI correlates of cognition in conventional MRI of normal-appearing brain in patients with clinical features of subacute combi...
متن کاملSubacute combined degeneration : report of two cases
Subacute combined degeneration ( SCD) due to vitamin B12 deficiency is common in North of Europe but sometimes it is seen in Iran. It can develop before the symptoms of anemia is obvious, with myelin injury and then axon and even neuron destruction in spinal cord, brain, optic and peripheral nerves. In this study two cases are reported; in the first patient, this disease in manifested by vitami...
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تاریخ انتشار 2017