Norfloxacin for the prophylaxis of travelers' diarrhea in U.S. military personnel.

نویسندگان

  • D A Scott
  • R L Haberberger
  • S A Thornton
  • K C Hyams
چکیده

Norfloxacin, an oral fluoroquinolone (dose 400 mg daily), was compared to a placebo in a double blinded randomized trial for the prophylaxis of travelers' diarrhea. The study was of U.S. Navy and Marine Corps personnel on shore leave in Alexandria, Egypt. A total of 222 subjects were available (105 norfloxacin, 117 placebo). In the placebo group, 26% (30/117) developed acute diarrhea vs. 2% (2/105) in the norfloxacin group. There were no significant side effects in either group.

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عنوان ژورنال:
  • The American journal of tropical medicine and hygiene

دوره 42 2  شماره 

صفحات  -

تاریخ انتشار 1990