Lymphocytes from Lupus Patients Activation and Is Overexpressed in T Agrin Signalling Contributes to Cell
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New role for Agrin in T cells and its potential importance in immune system regulation
Agrin plays a crucial role in the maintenance of the neuromuscular junction. However, it is expressed in other tissues as well, including T lymphocytes, where cell activation induces its expression. Agrin from activated T cells has the capacity to induce aggregation of key receptors and to regulate signalling. Interestingly, T cells isolated from patients with systemic lupus erythematosus over-...
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تاریخ انتشار 2007