Experimental Design for the Innervation of Tooth Forming from Implanted Cell Re-associations
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Immunomodulation Stimulates the Innervation of Engineered Tooth Organ
The sensory innervation of the dental mesenchyme is essential for tooth function and protection. Sensory innervation of the dental pulp is mediated by axons originating from the trigeminal ganglia and is strictly regulated in time. Teeth can develop from cultured re-associations between dissociated dental epithelial and mesenchymal cells from Embryonic Day 14 mouse molars, after implantation un...
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The innervation of teeth mediated by axons originating from the trigeminal ganglia is essential for their function and protection. Immunosuppressive therapy using Cyclosporine A (CsA) was found to accelerate the innervation of transplanted tissues and particularly that of bioengineered teeth. To avoid the CsA side effects, we report in this study the preparation of CsA loaded poly(lactic-co-gly...
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Because of their wide application in industries requiring high pressure and temperature, manufacturing square and rectangular pipes have attracted more attention than ever before. There are various methods such as extrusion, tensile and stress for manufacturing square pipes. Another method on which studies have focused in recent years is the re-forming of round pipes in order to turn them into ...
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Objectives- To assess the ectopic bone formation in canine masseter muscle following the implantation of the natural bovine bone minerals (NBM) loaded with canine mesenchymal stem cells (MSCs).Design- Experimental study.Animals- four mongrel dogs.Procedures- Tripotent MSCs isolated from the canine bone marrow were loaded onto the NBM sponges and allowed to adhere. The cell-loaded scaffolds were...
متن کاملRestoring physiological cell heterogeneity in the mesenchyme during tooth engineering.
Tooth development is controlled by reciprocal epithelial-mesenchymal interactions. Complete teeth can form when culturing and implanting re-associations between single embryonic dental epithelial and mesenchymal cells. Although epithelial histogenesis is clear, very little is known about cell diversity and patterning in the mesenchyme. The aim of this work was to compare the situation in engine...
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تاریخ انتشار 2018