Identification of Generalised (AA) Amyloidosis in an Arabian Gazelle (Gazella gazella sp.)

INTRODUCTION Amyloidosis has been previously documented in Dorcas and Mountain gazelles, most notably in a herd of Dorcas gazelles of the National Zoological Park in Washington8. The renal medulla was principally involved, leading to renal failure. In some cases there was more generalised involvement including the liver, spleen, adrenal glands and intestine. Studies have shown that this is of the reactive type (AA), which is believed to be derived from the acute phase protein SAA4. This case report identifies generalised AA amyloidosis in an Arabian gazelle in which there was glomerular and medullary deposition.