Ethanol Perturbs Glycosylation and Inhibits Hypersecretion in Trichoderma reesei.
نویسندگان
چکیده
The effects of ethanol and phenylethanol on the growth of and glycoprotein secretion by Trichoderma reesei were studied. Low levels (1.5%, vol/vol) of ethanol perturbed the glycosylation process, as shown by alterations in the isoelectric profile of the secreted proteins and a reduction in the rate of incorporation of mannose into oligosaccharides. In addition to these effects on posttranslational modification, ethanol drastically lowered the protein secretion level of a hypersecretory strain.
منابع مشابه
Glycoprotein hypersecretion alters the cell wall in Trichoderma reesei strains expressing the Saccharomyces cerevisiae dolichylphosphate mannose synthase gene.
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عنوان ژورنال:
- Applied and environmental microbiology
دوره 53 2 شماره
صفحات -
تاریخ انتشار 1987