Prevalence of neurogenetic disorders in the North of England
نویسندگان
چکیده
OBJECTIVE Genetic disorders enter the differential diagnosis of common neurologic diseases, but their overall prevalence is not known. We set out to determine their minimum prevalence. METHODS Meta-analysis of epidemiologic data gathered from the same geographic region in the North of England. RESULTS Monogenic neurologic disorders affect at least 90.9/100,000 (95% confidence interval 87.6-94.3), or 1 in 1,100 of the population in Northern England. CONCLUSION As a group, neurogenetic disorders are not rare. These findings have implications for clinical service delivery.
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عنوان ژورنال:
دوره 85 شماره
صفحات -
تاریخ انتشار 2015