reliminary Evidence That Hippocampal Volumes n Monkeys Predict Stress Levels of drenocorticotropic Hormone avid
نویسندگان
چکیده
ethods: Plasma ACTH levels were measured after restraint stress in 19 male monkeys pretreated with saline or hydrocortisone. Monkeys ere then randomized to an undisturbed control condition or intermittent social separations followed by new pair formations. After 17 onths of exposure to the intermittent social manipulations, restraint stress tests were repeated to determine test/retest correlations.
منابع مشابه
Early life stress and inherited variation in monkey hippocampal volumes.
BACKGROUND Opportunities for research on the causes and consequences of stress-related hippocampal atrophy are limited in human psychiatric disorders. Therefore, this longitudinal study investigated early life stress and inherited variation in monkey hippocampal volumes. METHODS Paternal half-siblings raised apart from one another by different mothers in the absence of fathers were randomized...
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OBJECTIVE Does stress damage the brain? Studies of adults with posttraumatic stress disorder have demonstrated smaller hippocampal volumes when compared with the volumes of adults with no posttraumatic stress disorder. Studies of children with posttraumatic stress disorder have not replicated the smaller hippocampal findings in adults, which suggests that smaller hippocampal volume may be cause...
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Hippocampal volume has been found to be smaller in individuals with stress-related disorders, but it remains unclear whether smaller volume is a consequence of stress or rather a vulnerability factor. Here, we examined this issue by relating stress levels to hippocampal volumes in healthy participants examined every 5 years in a longitudinal population-based study. Based on scores of 25- to 60-...
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Maternal separation and poor maternal care in animals have been shown to have important effects on the developing hippocampus and amygdala. In humans, children exposed to abuse/maltreatment or orphanage rearing do not present changes in hippocampal volumes. However, children reared in orphanages present enlarged amygdala volumes, suggesting that the amygdala may be particularly sensitive to sev...
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تاریخ انتشار 2007