Small for gestational age associated with short stature during adolescence.
نویسندگان
چکیده
This study examined the relationship between intrauterine growth retardation and adolescent stature in a sample of 1510 White subjects (754 males and 756 females) who were evaluated at birth and at the ages of 15, 16, and 17 years. The subjects were classified into two groups based on birthweight, small for gestational age (SGA) and appropriate for gestational age (AGA), corresponding respectively to values below the 10th, and between the 11th and 99th, percentiles of gestational age and sex. Results showed that boys and girls born prematurely (gestational age < 37 weeks of gestation) attained the same stature as those born at full term (>37 weeks of gestation). In contrast, those born SGA were significantly shorter than their counterparts born AGA. The average reduction in stature was 4.9 cm for males and 2.9 cm for females. When the analysis included adjustments for parental stature (and adolescent's age at menarche for females), the average reduction in stature equaled about 3.5 cm for males and 2.0 cm for females. It is thus concluded that the stature deficit reflects a reduction in growth rate rather than delay in maturation. © 1994 Wiley-Liss, Inc.
منابع مشابه
Hormonal regulation of postnatal growth in children born small for gestational age.
Children born small for gestational age (SGA) are at high risk of permanent short stature, with approximately 10% continuing to have stature below the third centile throughout childhood and adolescence and into adulthood. The mechanisms involved in catch-up growth, and those that prevent catch-up growth, are still unknown. To date, no reliable anthropometric or endocrine parameter predictive of...
متن کاملConcerns, expectations and perception regarding stature, physical appearance and psychosocial functioning before and during high-dose growth hormone treatment of short pre-pubertal children born small for gestational age.
BACKGROUND/AIMS Few data are available about parental concerns and psychosocial functioning of young children born small for gestational age (SGA) treated with growth hormone (GH). The present study focused on the perception of short stature and the concerns and expectations of the parents regarding GH treatment. METHODS Forty prepubertal short SGA children, randomized into a GH-treated and a...
متن کاملRECENT ADVANCES Should recombinant human growth hormone therapy be used in short small for gestational age children?
Short small for gestational age (SGA) children represent 20% of all children with short stature and therefore constitute a significant portion of the caseload in a growth clinic. The recent approval of recombinant human growth hormone (GH) for the treatment of short stature in SGA children by the European Union’s Committee on Proprietary Medicinal Products offers a new licensed therapeutic opti...
متن کاملShould recombinant human growth hormone therapy be used in short small for gestational age children?
Short small for gestational age (SGA) children represent 20% of all children with short stature and therefore constitute a significant portion of the caseload in a growth clinic. The recent approval of recombinant human growth hormone (GH) for the treatment of short stature in SGA children by the European Union's Committee on Proprietary Medicinal Products offers a new licensed therapeutic opti...
متن کامل[Growth of preterm-born children].
Children born prematurely might experience a period of growth restriction just after birth. Catch-up growth begins during the first months of life and can be slow and progressive. These children may remain shorter and thinner throughout infancy and childhood compared to children born at term. In some cases, complete catch-up growth occurs only during adolescence. However, some children do not c...
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عنوان ژورنال:
- American journal of human biology : the official journal of the Human Biology Council
دوره 6 3 شماره
صفحات -
تاریخ انتشار 1994