Guidelines on gamma irradiation of blood components for the prevention of transfusion-associated graft-versus-host disease. BCSH Blood Transfusion Task Force.
نویسندگان
چکیده
Prepared by the BCSH Blood Transfusion Task Force (Chairman: D. Voak). Membership: J. Chapman, R. D. Finney, K. Forman, P. Kelsey, S. M. Knowles, J. A. F. Napier, P. Phillips, R. Mitchell, M. F. Murphy, A. H. Waters and J. K. Wood. Working Party: L. M. Williamson (Convener), T. Baglin, A. Copplestone, P. Dendy, K. Forman, B. Gibson, S. Knowles, G. Morgan, D. Norfolk, A. Richards, A. Todd, R. Warwick, D. Webb
منابع مشابه
Guidelines on the use of irradiated blood components prepared by the British Committee for Standards in Haematology blood transfusion task force.
Search terms included: Transfusion-associated graft-versus-host disease, Transfusion-associated graft-versus-host, TA-GvHD. The last guideline covering this topic was published in 1996 (British Committee for Standards in Haematology (BCSH) Blood Transfusion Task Force, 1996. The writing group produced the new draft guideline, which was subsequently revised by consensus by members of the Haemato...
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T he prevention of transfusion-associated graftversus-host disease (TA-GVHD) is critical for the reduction of transfusion-related risks. Because this complication of transfusion is difficult to treat and, consequently, has a high mortality rate, the optimal approach to management of TA-GVHD is prevention. TA-GVHD is associated with the transfusion of cellular blood products (blood components th...
متن کاملTreatment of whole blood with riboflavin plus ultraviolet light, an alternative to gamma irradiation in the prevention of transfusion-associated graft-versus-host disease?
BACKGROUND Exposure of blood products to gamma irradiation is currently the standard of care in the prevention of transfusion-associated graft-versus-host disease (TA-GVHD). Regulatory, technical, and clinical challenges associated with the use of gamma irradiators are driving efforts to develop alternatives. Pathogen reduction methods were initially developed to reduce the risk of microbial tr...
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Transfusion associated graft versus host disease(GVHD) is a serious clinical complication that occurs in some cases after blood and blood products transfusion. The mortality ratio of this disorder is very high and in over 90% of cases lead to patients’ death. The procedure routinely used to inhibit GVHD is inactivation of donor blood lymphocytes and prevention of their proliferation in recipien...
متن کاملTransfusion-associated graft-versus-host disease
Transfusion-associated graft-versus-host disease (TA-GVHD) is a rare but almost uniformly lethal complication of blood transfusion. Although the graft-versus-host disease (GVHD) that occurs after allogeneic bone marrow transplantation and TA-GVHD share some clinical similarities, GVHD after bone marrow transplant is not uncommon and often responds positively to immunosuppression. The much rarer...
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عنوان ژورنال:
- Transfusion medicine
دوره 6 3 شماره
صفحات -
تاریخ انتشار 1996