Acute pulmonary hypertensive crisis in a patient with primary pulmonary hypertension treated by both epoprostenol (prostacyclin) and nitroprusside.
نویسندگان
چکیده
A 19-year-old girl was diagnosed as having primary pulmonary hypertension that was confirmed by right heart catheterization. Acute right heart failure was associated with syncope. Stabilization, while not achieved with intravenous epoprostenol (Prostacyclin) alone, was achieved with intravenous prostacyclin and nitroprusside.
منابع مشابه
Prostacyclin and acetylcholine as screening agents for acute pulmonary vasodilator responsiveness in primary pulmonary hypertension.
Epoprostenol sodium (prostacyclin) administered intravenously is considered the standard for assessing the ability of the pulmonary circulation to vasodilate. At present, epoprostenol sodium is an investigational drug that has limited availability. In contrast, acetylcholine, also a pulmonary vasodilator, is readily available. Therefore, we assessed the feasibility of using acetylcholine as an ...
متن کاملProstacyclin (epoprostenol) and heart-lung transplantation as treatments for severe pulmonary hypertension.
OBJECTIVE To determine whether epoprostenol (prostacyclin, PGI2) or heart-lung transplantation (HLT), or both improves survival of patients with severe pulmonary hypertension. DESIGN This was a prospective study where the effects of epoprostenol were compared with conventional treatment. Also, the benefits of epoprostenol and HLT were assessed by comparing survival in this group with that of ...
متن کاملScreening Agents for Acute Pulmonary Vasodilator Responsiveness in Primary Pulmonary Hypertension
a pulmonary vasodilator, is readily available. Therefore, we assessed the feasibility of using acetylcholine as an alternative to prostacyclin in testing for the capacity of the pulmonary vasculature to vasodilate. Twenty-three patients with primary pulmonary hypertension (mean pulmonary arterial pressure, 58.5±13.4 mm Hg) received incremental infusions of prostacyclin and acetylcholine to pred...
متن کامل[Ten years' experience in continuous intravenous epoprostenol therapy in severe pulmonary arterial hypertension].
INTRODUCTION Primary pulmonary hypertension and its associated forms is a progressive and often fatal disease, the course of which has been favourably modified by prostacyclin therapy in the last decade. OBJECTIVE The aim of this study is to analize retrospectively the efficacy of continuous intravenous epoprostenol (synthetic prostacyclin) therapy in pulmonary arterial hypertension, and to c...
متن کاملStreptococcal skin infections.
1. Rich S, Kaufmann E, Levy PS. The effect of high doses of calcium-channel blockers on survival in primary pulmonary hypertension. N Engl J Med 1992;327:76-81. 2. Rubin LJ, Mendoza J, Hood M, et al. Treatment of primary pulmonary hypertension with continuous intravenous prostacyclin (epoprostenol): results of a randomized trial. Ann Intern Med 1990;112:485-91. 3. Barst RJ, Rubin LJ, McGoon MD,...
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عنوان ژورنال:
- Chest
دوره 99 5 شماره
صفحات -
تاریخ انتشار 1991