Inter-VH-gene-family shared idiotype on acquired immunodeficiency syndrome-associated lymphomas.

To the Editor: of 178 (6.2%) cases of non-acquired immunodeficiency syndrome (AIDS) B-cell lymphomas.' We were interested in determining if Lymphomas occurring in individuals infected with the human B-cell lymphomas occurring in HIV-l-infected individuals similarly immunodeficiency virus type 1 (HIV-l), are predominantly of Bexpressed shared idiotypes. We immunohistochemically stained 25 cell origin. Tumors of B-cell origin not occurring in HIV1 -infected separate AIDS-associated B-cell lymphomas with a panel of antiindividuals have been shown to express shared idiotypes; in particuidiotypes (generous gift of Rich Miller, IDEC Pharmaceuticals, lar, one anti-idiotype, S2.33, reacted with the leukemic cells of 8 of Mountain View, CA); the S2.33 idiotype reacted with 7 (28%) (ie, 105 (7.6%) cases of chronic lymphocytic leukemias (CLL) and 11 1 of 7 Burkitt's lymphomas, 4 of 16 immunoblastic lymphomas,