Plasticity of the asialoglycoprotein receptor deciphered by ensemble FRET imaging and single-molecule counting PALM
نویسندگان
چکیده
The Eunice Kennedy Shriver National Institute of Child Health and Human Development, Cell Biology and Metabolism Branch 1: Section on Organelle Biology 2: Unit on Cellular Polarity National Institutes of Health, 18 Library Drive, Bethesda, MD 20892, USA 3: Department of Biophysics and Cell Biology, Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary. * Corresponding author email: [email protected] Manuscript number: #2012-11753
منابع مشابه
Plasticity of the asialoglycoprotein receptor deciphered by ensemble FRET imaging and single-molecule counting PALM imaging.
The stoichiometry and composition of membrane protein receptors are critical to their function. However, the inability to assess receptor subunit stoichiometry in situ has hampered efforts to relate receptor structures to functional states. Here, we address this problem for the asialoglycoprotein receptor using ensemble FRET imaging, analytical modeling, and single-molecule counting with photoa...
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تاریخ انتشار 2012