Beta-blockers and diuretics in antihypertensive therapy: the debate continues.

Antihypertensive Therapy: Beta-Blockers and Diuretics - What is the Evidence?

Antihypertensive therapy: beta-blockers and diuretics-why do physicians not always follow guidelines?

BUMC PROCEEDINGS 2000;13:128–131 T he most recent reports of the Joint National Committee (JNC VI) and the World Health Organization recommend beta-blockers and diuretics as first-line therapy for uncomplicated essential hypertension (1, 2). Similar recommendations have been issued over the past few years by many authoritative sources and influential journals. These recommendations were suppose...

Antihypertensive therapy among newly treated patients: An analysis of adherence and cost of treatment over years

OBJECTIVE To perform a time-trend analysis of adherence and cost of antihypertensive treatment over four years. METHODS A population-based retrospective cohort study was conducted. We included subjects ≥18 years, and newly treated for hypertension with diuretics, beta-blockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, or angiotensin receptor blockers between 01 Janu...

Choosing initial therapy for hypertension. A personal view.

With numerous safe and effective antihypertensive drugs now available, the clinician should no longer choose only diuretic agents or beta-adrenergic receptor blockers (beta-blockers) as initial therapy. Five classes of agents, including angiotensin converting enzyme inhibitors, beta-blockers, calcium entry blockers, peripheral alpha 1-adrenergic receptor blockers, and thiazide diuretic agents, ...

Fluid matters in choosing antihypertensive therapy: a hypothesis that the data speak volumes.

Assuming that blood pressure is lowered equivalently, diuretics are more effective than angiotensin-converting enzyme inhibitors (ACEIs), calcium channel blockers (CCBs), and alpha-adrenergic receptor blockers (alpha-blockers) at preventing heart failure, and they are more effective than ACEIs and alpha-blockers at preventing strokes. Compared with beta-adrenergic receptor blockers (beta-blocke...