Structural variability of large and small chondroitin sulphate/dermatan sulphate proteoglycans.
نویسندگان
چکیده
Ledbetter, S. R., Tyree, B.. Hashell. J. R. & Horrigan. E. A. ( 1985) J . Biol. C'hrm. 260,8106-8 I 13 Hassell, J. R., Noonan, D. M., Ledbetter, S. R. & Laurie. G. W. (1986) C'ihri Found. Symp. 124,204-222 Noonan. D. M.. Horrigan. E. A.. Ledbetter. S. R.. Vogeli. G., Sasaki. M.. Yamada. Y. & Hassell. J . R. ( 1988) J . Riol. ('hem. 263, 16379-16387 Paulsson. M.. Yurchenko. P. D.. Ruben. G. C.. Engel. J. & Timpl, R. ( 1987) J . Mol. Biol. 197,297-3 I3 Clement, B.. Seyui-Real, B., Hassell, J. R.. Martin, G. R. &i Yamada. Y. ( 19891 J . Biol. C'hem. 264. 124671247 1 Biol. 189,205-216
منابع مشابه
Immunochemical and biochemical comparisons between embryonic chick bone marrow and epiphyseal cartilage chondroitin/dermatan sulphate proteoglycans.
Chrondroitin sulphate proteoglycans obtained from embryonic chick bone marrow and epiphyseal cartilage were compared using immunochemical and biochemical analyses. Proteoglycans from each tissue, separated on CsCl density gradients, under dissociative conditions, into high (1.6 g ml-1), medium (1.5 g ml-1) and low (1.4 g ml-1) buoyant density fractions, were immunochemically analysed, using a p...
متن کاملThe synthesis of dermatan sulphate proteoglycans by fetal and adult human articular cartilage.
Non-aggregating dermatan sulphate proteoglycans can be extracted from both fetal and adult human articular cartilage. The dermatan sulphate proteoglycans appear to be smaller in the adult, this presumably being due to shorter glycosaminoglycan chains, and these chains contain a greater proportion of their uronic acid residues as iduronate. Both the adult and fetal dermatan sulphate proteoglycan...
متن کاملDermatan sulphate proteoglycans from sclera examined by rotary shadowing and electron microscopy.
Two dermatan sulphate-containing proteoglycans from bovine sclera were examined by rotary shadowing and electron microscopy, and the results were compared with previous biochemical findings. Both the large iduronate-poor proteoglycan (PGI) and the small iduronate-rich proteoglycan (PGII) possessed a globular proteinaceous region. Whereas PGI had a branched extension from the globular region, wi...
متن کاملDomains in cartilage proteoglycans: do they define function?
Proteoglycans ( PGs) have, until recently, been poorly characterized at the amino acid sequence level. Since 1985, when the first proteoglycan core protein structure was determined 1 11, structural information on these complex molecules has become relatively plentiful. Proteoglycans are a good example of protein construction through the assembly of domains. It is tempting to assume that the ind...
متن کاملStructure and properties of dermatan sulphate proteoglycans.
Introduction Fibrous connective tissues like sclera, skin, tendon and cornea have a high content of collagen but only small amounts of proteoglycans and structural glycoproteins. The specific blend of collagen and proteoglycan types determines the properties of the tissue. The proteoglycans are characterized by having a central protein core substituted by one or several glycosaminoglycan chains...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Biochemical Society transactions
دوره 18 2 شماره
صفحات -
تاریخ انتشار 1990