19 Endophthalmitis

نویسندگان

  • Phillip S. Coburn
  • Michelle C. Callegan
چکیده

Endophthalmitis is an infection of the anterior and posterior segments of the eye resulting from the introduction of microorganisms following a surgical procedure (postoperative), traumatic penetrating injury (posttraumatic), or metastasis from an infection of a distant site in the body (endogenous). Endophthalmitis can develop into panophthalmitis if the infectious agent invades the cornea and sclera. The vast majority of cases of endophthalmitis result from intraocular surgical procedures, in particular cataract surgery (West et al., 2005). Over the past several decades, the number of postoperative endophthalmitis cases has risen steadily, owing to the increase in the number of invasive ocular surgeries performed (West et al., 2005). The etiological agents responsible for endophthalmitis include both Grampositive and Gram-negative bacteria and fungi. Cases of post-surgical endophthalmitis are usually a result of the introduction of members of the normal microbiota of the eyelid and skin surrounding the eye, the most common cause being coagulase-negative staphylococci (CNS) (West et al., 2005). Cases of posttraumatic endophthalmitis are more frequently caused by environmental bacteria, the most common being Staphylococcus aureus and Bacillus cereus (Jonas et al., 2000; Meredith, 1999; O’Brien & Choic, 1995; Thompson et al., 1993). Frequent causes of endogenous endophthalmitis (EE) include S. aureus, streptococcal species, B. cereus, and Gram-negative bacteria including Klebsiella pneumoniae, Escherichia coli, and fungal agents such as Candida albicans (Greenwald et al., 1986; Jackson et al., 2003; Okada et al., 1994; Romero et al., 1999; Shammas, 1977; Shrader et al., 1990).

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تاریخ انتشار 2012