Transcriptional regulation: Kamikaze activators

نویسندگان

  • Dominique Thomas
  • Mike Tyers
چکیده

Transcription factors are often targeted for rapid degradation by the ubiquitin-proteasome system. Recent evidence points to a correlation between the potency and instability of transcriptional activators, suggesting a possible direct role for ubiquitin-dependent proteolysis in transcriptional activation.

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عنوان ژورنال:
  • Current Biology

دوره 10  شماره 

صفحات  -

تاریخ انتشار 2000