Vascular perfusion abnormalities in infants with spinal muscular atrophy.
نویسندگان
چکیده
Spinal muscular atrophy (SMA) is an important cause of death in children and SMA type I, also known as Werdnig-Hoffman disease, is the most severe form of this disease. We report 2 cases of infants with SMA I in whom a distal necrosis developed, a feature not previously reported. Poor perfusion, autonomic dysfunction, and position-dependent factors may all play a role in the development of this complication.
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عنوان ژورنال:
- The Journal of pediatrics
دوره 155 2 شماره
صفحات -
تاریخ انتشار 2009