PPARδ Agonism for the Treatment of Obesity and Associated Disorders: Challenges and Opportunities

New Hopes and Challenges for Treatment of Neurodegenerative Disorders: Great Opportunities for Young Neuroscientists

A Systematic Review Opportunities and Challenges of Tele-cardiology in Health Care Systems

Aim: Telecardiology provides a useful diagnostic tool for accurate and rapid diagnosis of patients with cardiac disorders to specialist and general practitioners. In this study, a systematic review was conducted to identify effective components and approaches in Telecardiology, such as the opportunities and challenges of applying this system in different domains. Information sources or data: T...

Identifying the Potentials, Challenges, and Barriers to the Application of New Communication Technologies in the Field of Health with a Focus on Rare Patients: A Qualitative Study

Introduction: Advances in new communication technologies have created a good environment for the provision of various services. Due to the importance of using new communication technologies in health care, this study was conducted to identify opportunities, threats, strengths, and weaknesses of these technologies in the field of health with a focus on rare patients. Method: This qualitative st...

A peroxisome proliferator-activated receptor-δ agonist provides neuroprotection in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease

Peroxisome proliferator-activated receptor (PPAR)-γ and PPARα have shown neuroprotective effects in models of Parkinson's disease (PD). The role of the third, more ubiquitous isoform PPARδ has not been fully explored. This study investigated the role of PPARδ in PD using 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) to model the dopaminergic neurodegeneration of PD. In vitro administratio...

Pmn-15: The Role of Lifestyle Modification in Management of Overweight Infertile Women with Polycystic Ovary Syndrome

Background: Polycystic ovary syndrome (PCOS) is a complex, heterogeneous disorder of uncertain etiology, with a prevalence of up to 10% and frequently associated with obesity, with at least 50% of women with polycystic ovary syndrome demonstrating overweight or obesity defined by body mass index >25 or >30 kg/m2. The syndrome is associated with numerous morbidities, including infertility, obste...