Use of proton pump inhibitors during pregnancy and breastfeeding.

نویسندگان

  • Alejandro A Nava-Ocampo
  • Elvia Y Velázquez-Armenta
  • Jung-Yeol Han
  • Gideon Koren
چکیده

QUESTION A 36-year-old pregnant patient has symptoms of peptic disease. Treatment with diet and lifestyle modifications and also antacids has given her little relief. If she were not pregnant, I would prescribe a proton pump inhibitor (PPI) for her. She is now 4 weeks pregnant, and I need to determine whether PPIs are safe during pregnancy. ANSWER Data currently available suggest that omeprazole is not teratogenic in humans. While information on other PPIs is limited, a systematic review of the evidence suggests that they are also not teratogenic.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Safety and Efficiency of Proton Pump Inhibitors during Pregnancy and Conception.

W e live in a constantly changing world and due to stress, bad eating habits and Helicobacter Pylori (HP) infections, and we tend to auto medicate ourselves with different proton pump inhibitors (PPIs) in order to cure our “heart burns”. But what happens if we are young and are trying to procreate? What are the side effects and the incidence of severe birth defects after PPIs use during pregnan...

متن کامل

Pantoprazole, a proton pump inhibitor, increases orthodontic tooth movement in rats

Objective(s):Pantoprazole, is a proton pump inhibitor (PPI) prescribed for the treatment of upper gastrointestinal disorders, which in high doses has been suggested to decrease calcium absorption leading to hypocalcaemia and therefore osteoporosis. The aim of this study was to assess whether pantoprazol, could alter the rate of orthodontic tooth movement (OTM) in rats. Materials and Methods: A ...

متن کامل

Clinical points of intravenous pantoprazole consumption in Cardiac ICU

Background: Proton pump inhibitors (PPIs) are the most common medicine for the treatment and prophylaxis of acid peptic conditions. The inappropriate use of the PPIs mainly intravenous form of Pantoprazole may lead to excessive cost and unexpected adverse effect. The purpose of our study was to evaluation the use of intravenous Pantoprazole in international heart center in north of Iran. Meth...

متن کامل

Chronic Asthma and Gastro-Esophageal Reflux Disease: The Treatment Plans

Gastro-esophageal reflux disease (GERD) regularly occurs when stomach acid moves up from the stomach into the esophagus. GERD might be associated with chronic asthma symptoms such as coughing and breathlessness. According to several studies on children and adults, GERD is proven to have a close relationship with asthma.  Medication treatment via proton-pump inhibitors (PPIs), such as Omeprazole,...

متن کامل

Treatment of heartburn and acid reflux associated with nausea and vomiting during pregnancy.

QUESTION In addition to suffering from nausea and vomiting of pregnancy, which is being treated with antiemetics, some of my pregnant patients complain of heartburn and acid reflux. Should these symptoms also be treated and, if so, which acid-reducing medications are safe for use during pregnancy? ANSWER Increased severity of nausea and vomiting of pregnancy is associated with the presence of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Canadian family physician Medecin de famille canadien

دوره 52  شماره 

صفحات  -

تاریخ انتشار 2006