Effects of puff-adder venom on coagulation, fibrinolysis and platelet aggregation in the baboon.
نویسندگان
چکیده
The in vitro and in vivo haematological effects of puffadder (Bitis arietans) venom in the baboon (Papio ursinus) with regard to its effect on coagulation, fibrinolysis and platelet aggregation were studied. There is a delay in the intrinsic coagulation mechanism with fibrinolysis and in vitro fibrinogenolysis. Normal human platelets demonstrated an extreme susceptibility to puff-adder venom in vitro. The aggregation of platelets with small dosages of venom was irreversible.
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عنوان ژورنال:
- South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
دوره 48 28 شماره
صفحات -
تاریخ انتشار 1974