Sigma L is important for cold shock adaptation of Bacillus subtilis.
نویسندگان
چکیده
Although sigma factor-dependent transcriptional regulation was shown to be essential for adaptation to different environmental stimuli, no such sigma factor has been related to the regulation of the cold shock response in Bacillus subtilis. In this study, we present genetic evidence for participation of sigma(L) (sigma(54)) and the two sigma(L)-dependent transcriptional enhancers BkdR and YplP in the cold shock response of Bacillus subtilis JH642. Single-gene deletion of either sigL, bkdR, or yplP resulted in a cold-sensitive phenotype.
منابع مشابه
Cold shock response in Bacillus subtilis.
Following a rapid decrease in temperature, the physiology of Bacillus subtilis cells changes profoundly. Cold shock adaptation has been monitored at the level of membrane composition, adjustment in DNA topology, and change in cytosolic protein synthesis/composition. Some major players in these processes (cold-stress induced proteins and cold acclimatization proteins, CIPs and CAPs) have been id...
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عنوان ژورنال:
- Journal of bacteriology
دوره 188 8 شماره
صفحات -
تاریخ انتشار 2006