Treponema pallidum fibronectin-binding proteins.
نویسندگان
چکیده
Putative adhesins were predicted by computer analysis of the Treponema pallidum genome. Two treponemal proteins, Tp0155 and Tp0483, demonstrated specific attachment to fibronectin, blocked bacterial adherence to fibronectin-coated slides, and supported attachment of fibronectin-producing mammalian cells. These results suggest Tp0155 and Tp0483 are fibronectin-binding proteins mediating T. pallidum-host interactions.
منابع مشابه
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ورودعنوان ژورنال:
- Journal of bacteriology
دوره 186 20 شماره
صفحات -
تاریخ انتشار 2004