Practicalities of using an adaptive design for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests
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چکیده
Practicalities of using an adaptive design for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests Janet Dunn, Andrea Marshall, Amy Campbell, David Cameron, Helena Earl, Iain Macpherson, Christopher Poole, Daniel Rea, Adele Francis, Victoria Harmer, Adrienne Morgan, Nigel Stallard, Andreas Makris, Luke Hughes-Davies, Robert Stein
منابع مشابه
Using adaptive designs for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests
Methods OPTIMA prelim, the feasibility phase, aims to recruit 300 patients to evaluate performance and health-economics of a number of multi-parameter tests to identify test(s) to be used in the main trial and to establish the acceptability to patients and clinicians of randomisation. Patients are randomised to the standard arm or to the “test-directed treatment” arm according to the result of ...
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عنوان ژورنال:
دوره 16 شماره
صفحات -
تاریخ انتشار 2015