Immunity in the Swedish population: diphtheria, tetanus and poliomyelitis.
BACKGROUND Large-scale vaccination programmes have been carried out for a long time in Sweden, as in many other countries. However, often little is known of the effects of these vaccinations. During 1990 and 1991 a survey of immunity based on a random adult population sample was carried out. The main purpose was to estimate the level of immunity to diphtheria, tetanus and polio of the adult population in Sweden. In total 4800 people were randomly selected according to a stratified, two-stage, sampling plan. METHODS Based on standard sampling theory, methods for calculations of estimates and confidence intervals of the proportion of the population that is immune are given. The response patterns and its possible effects on the estimates are discussed. RESULTS In total, 70.6% of the 4800 selected gave a blood sample. The response rate differs for men and women and for different age groups. Among the oldest, the response rate was close to 80%, but it was only about 60% among the youngest. CONCLUSIONS With the survey design used, it was possible to obtain a sufficient degree of response. Our experience is that the response rate depends to a large extent on the efforts made to explain and motivate participation.
BACKGROUND During 1990 and 1991 a survey of immunity was carried out in Sweden. The main purpose was to estimate the level of immunity to diphtheria, tetanus and polio in the adult population. In total, 4800 people, randomly selected according to a stratified, two-stage, sampling plan, were contacted and asked to contribute a blood sample. Of those selected, 70.6% gave a blood sample. METHODS...متن کامل
Seroprevalence and determinants of diphtheria, tetanus and poliomyelitis antibodies among adults in Berlin, Germany.
The immunity levels against diphtheria, tetanus and poliomyelitis were investigated among blood donors (n = 2079) in Berlin. Of all participants, only 60% had full, long-term protection against diphtheria, 72% against tetanus, 87% against poliomyelitis type 1, 77% against poliomyelitis type 2 and 73% against type 3. There was a striking decrease of tetanus and diphtheria immunity levels by age....متن کامل
Patients with systemic inflammatory and autoimmune diseases are at risk of vaccine-preventable illnesses.
OBJECTIVE To evaluate vaccine coverage and humoral immunity to tetanus, diphtheria and poliomyelitis in adults followed for systemic inflammatory and/or autoimmune diseases (SIADs). METHODS A cross-sectional study was conducted between June and August 2006 in a monocentric cohort of adults with SIAD. A standardized questionnaire was administered to collect medical, therapeutic and vaccine cov...متن کامل
A survey of titres of diphtheria and tetanus antitoxins and of antibodies to polioviruses in the sera of 291 schoolchildren aged 15, 11, and 7 years showed that high immunisation rates can evoke protective concentrations of tetanus antitoxin in 98% of children and protective levels of the antibodies to diphtheria and all three types of poliomyelitis in 85% of children. Reinforcing immunisation ...متن کامل