Fusion of the envelope of mucous droplets with the luminal plasma membrane in acinar cells of the cat submandibular gland
نویسندگان
چکیده
The release of mucus from acinar cells of the cat submandibular gland was examined by electron microscopy. The limiting membrane of mucous droplets fuses with the luminal plasma membrane to form a five-layered contact. This is converted to a three-layered membrane (unit membrane) by avulsion of the plasmalemma. Attenuation and rupture of this membranous barrier permits the contents of the mucous droplets to flow into the lumen.
منابع مشابه
The human submandibular gland: immunohistochemical analysis of SNAREs and cytoskeletal proteins.
Submandibular acinar glands secrete numerous proteins such as digestive enzymes and defense proteins on the basis of the exocrine secretion mode. Exocytosis is a complex process, including a soluble NSF attachment protein receptor (SNARE)-mediated membrane fusion of vesicles and target membrane and the additional activation of cytoskeletal proteins. Relevant data are available predominantly for...
متن کاملبررسی ایمونوهیستوشیمیایی بروز نشانگر E- cadherin در تومورهای بزاقی پلئومورفیک آدنوما و موکواپیدرموئید کارسینوما
Objective: E-cadherin is a classic cadherin that plays a key role in epithelial cell adhesion. This protein is being referred to as the suppressor of proliferation and invasion. Limited studies have investigated E-cadherin expression in salivary gland neoplasms. This study sought to assess the expression of E-cadherin and its possible role in progression and invasion of salivary gland neoplasms...
متن کاملInteraction of lithium and gentamicin in salivary gland by electron microscopy and protein and DNA measurement
The effects of gentamicin, lithium and combination of these drugs on ultrastructural morphology of rat submandibular glands were studied. Daily intraperitoneal injection of 40 mg/kg of gentamicin which causes chronic salivary gland toxicity, led to a marked decrease in gland's dry weight and total protein concentration but did not affect DNA content. Electron micrograph (EM) of submandibular ...
متن کاملThe Regulatory Role of Rolipram on Inflammatory Mediators and Cholinergic/Adrenergic Stimulation-Induced Signals in Isolated Primary Mouse Submandibular Gland Cells.
Exposure to bacterial lipopolysaccharides (LPS) induces inflammatory signals in salivary glands. We investigated the regulatory role of phosphodiesterase 4 (PDE4) inhibitor rolipram on inflammatory mediators and cholinergic/adrenergic stimulation-induced intracellular Ca(2+) signaling in salivary acinar and ductal cells. Submandibular gland (SMG) expressed PDE4A through 4D mRNA and PDE4 was loc...
متن کاملThe submandibular salivary gland microscopic morphology of the adult African giant pouched rat (Cricetomys gambianus, waterhouse-1840)
BACKGROUND: In the present study, the submandibularsalivary gland microscopic morphology of the adult Africangiant pouched rat was investigated. This study was carried out toprovide the basic histology of this organ in the giant pouched rat,to accompany the dearth of information of its microscopicarchitecture in the available literature. This becomes of evenhigher importance when considering th...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of Cell Biology
دوره 68 شماره
صفحات -
تاریخ انتشار 1976