Target Fishing: A Single-Label or Multi-Label Problem?
نویسندگان
چکیده
Background: According to Cobanoglu et al and Murphy, it is now widely
منابع مشابه
A multi-label approach to target prediction taking ligand promiscuity into account
BACKGROUND According to Cobanoglu et al., it is now widely acknowledged that the single target paradigm (one protein/target, one disease, one drug) that has been the dominant premise in drug development in the recent past is untenable. More often than not, a drug-like compound (ligand) can be promiscuous - it can interact with more than one target protein. In recent years, in in silico target p...
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عنوان ژورنال:
- CoRR
دوره abs/1411.6285 شماره
صفحات -
تاریخ انتشار 2014