Prenatal allergen and diesel exhaust exposure and their effects on allergy in adult offspring mice

Evaluation of the Protective Effect of Astaxanthin Against Undesired Effects of Prenatal Bacterial Lipopolysaccharide (LPS) Exposure on Maternal Behaviors and Neuronal Changes of Adult Male Offspring in NMRI Mice

Background: Prenatal bacterial lipopolysaccharides (LPS) exposure causes damage of the brain and gonadal system.The aim of this study included determination of astaxanthin effect to ameliorate undesired effects of bacterial LPS during fetal period and improve maternal behavior, body weight and length and neural changes in adult male NMRI mice. Methods: Pregnant female mice were divided into fou...

Effects of Prenatal Lipopolysaccharide Exposure on Reproductive Activities and Serum Concentrations of Pituitary-Gonadal Hormones in Mice Offspring

Social Isolation-Induced Territorial Aggression in Male Offspring Is Enhanced by Exposure to Diesel Exhaust during Pregnancy

Diesel exhaust particles are a major component of ambient particulate matter, and concern about the health effects of exposure to ambient particulate matter is growing. Previously, we found that in utero exposure to diesel exhaust affected locomotor activity and motor coordination, but there are also indications that such exposure may contribute to increased aggression in offspring. Therefore, ...

Exposure to allergen and diesel exhaust particles potentiates secondary allergen-specific memory responses, promoting asthma susceptibility.

BACKGROUND Exposure to traffic pollution particulate matter, predominantly diesel exhaust particles (DEPs), increases the risk of asthma and asthma exacerbation; however, the underlying mechanisms remain poorly understood. OBJECTIVE We sought to examine the effect of DEP exposure on the generation and persistence of allergen-specific memory T cells in asthmatic patients and translate these fi...

The Effect of Prenatal Exposure to Restraint Stress on Hippocampal Granule Neurons of Adult Rat Offspring

Objective(s) It is well known that prenatal stresses (PS) induce a variety of neurobiological and behavioral alterations, some of them involving the hippocampal formation. This study aimed to determine whether restraint stress influences the neuronal volume and number of granule cells in the hippocampus of adult rat offspring. Materials and Methods Ten Wistar pregnant rats were randomly divi...