3-(Piperidin-1-yl)-6-(1H-pyrazol-1-yl)pyridazine
نویسندگان
چکیده
In the title compound, C(12)H(15)N(5), the piperidine ring adopts a chair conformation with the substituent C atom in an equatorial site and the dihedral angle between the pyridazine and pyrazole ring planes is 10.36 (2)°.
منابع مشابه
3-Chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine
In the title compound, C(9)H(9)ClN(4), the dihedral angle between the aromatic rings is 6.25 (9)°. The whole mol-ecule is approximately planar (r.m.s. deviation = 0.070 Å). In the crystal, π-π inter-actions between the centroids of the pyridazine rings [separation = 3.5904 (10) Å] occur.
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The title solvated salt, C21H17N7 (2+)·SO4 (2-)·CH3OH, was obtained when we attempted to prepare the complex of ferrous sulfate and 2,6-bis-[3-(pyridin-2-yl)-1H-pyrazol-1-yl]pyridine in methanol. The dihedral angles between adjacent pyridine and pyrazole rings range from 3.8 (1) to 13.4 (1)°. An intra-molecular N-H⋯N hydrogen bond occurs. In the crystal, N-H⋯O and O-H⋯N hydrogen bonds between s...
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In the title compound, [Mn(C(8)H(3)NO(6))(C(8)H(7)N(3))(2)(H(2)O)]·0.5H(2)O, the Mn(2+) ion is octa-hedrally coordinated by two 2-(1H-pyrazol-3-yl)pyridine ligands, one 4-nitro-phthalate ligand and one coordinated water mol-ecule leading to an overall MnN(4)O(2) coordination environment. The two 2-(1H-pyrazol-3-yl)pyridine ligands, which deviate from planarity by 0.0187 (2) and 0.0601 (2) Å, ma...
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New novel derivatives of N-((5-((6-oxido-6-(4 substituted phenoxy)-4,8-dihydro-1H-[1,3,2] dioxaphosphepino [5,6-c]pyrazol-1-yl) methyl)-1,3,4-thiadiazol-2-yl)carbamoyl) substituted benzene sulfo namides (7a-o as depicted in scheme) were Synthesized by condensation reaction of 4substituted Phenyl phosphorodichloridates (6a-c) and N-((5-((4,5-bis(hydroxymethyl)-1H-pyrazol-1-yi)methyl)1,3,4-thiadi...
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4-Aminoantipyrine was utilized as key intermediate for the synthesis of pyrazolone derivatives bearing biologically active moieties. The newly synthesized compounds were characterized by IR, 1H- and 13C-NMR spectral and microanalytical studies. The compounds were screened as anticancer agents against a human tumor breast cancer cell line MCF7, and the results showed that (Z)-4-((3-amino-5-imino...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2010