Oxygen Uptake during the Hela Cell Life Cycle and Its Correlation with Macromolecular Synthesis

There have been several reports on the utilization of oxygen during the cell life cycle (1-7), with particular emphasis on the question of whether there is any change during mitosis . One of the most elegant of these studies, the "Cartesian Diver" experiments of Holter and Zeuthen (1) on synchronous egg cells, indicated that the oxygen requirement was decreased in mitosis . While Scholander et al . (2, 3) have challenged these results, earlier work of Erickson (4), and Stern and Kirk (5) on synchronous microspores of Lilium and Trillium, respectively, confirm them ; and