CTCF, WAPL and PDS5 proteins control the formation of TADs and loops by cohesin

اسناد مشابه

• Topologically associating domains and chromatin loops depend on cohesin and are regulated by CTCF, WAPL, and PDS5 proteins

  مقاله‌ی دسترسی آزاد۲۰۱۷The EMBO JournalGordanaWutz, CsillaVárnai, KotaNagasaka, David ACisneros

• Computational prediction of CTCF/cohesin-based intra-TAD loops that insulate chromatin contacts and gene expression in mouse liver

  مقاله‌ی دسترسی آزاد۲۰۱۸eLifeBryan JMatthews, David JWaxman

• Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2

  سند علمی۲۰۱۰The Journal of cell biologyKang Zeng, Ricardo Nunes Bastos, Francis A. Barr, Ulrike Gruneberg

  Many protein kinases are activated by a conserved regulatory step involving T-loop phosphorylation. Although there is considerable focus on kinase activator proteins, the importance of specific T-loop phosphatases reversing kinase activation has been underappreciated. We find tha

• Protein phosphatase 6 regulates mitotic spindle formation by controlling the T-loop phosphorylation state of Aurora A bound to its activator TPX2

  مقاله‌ی دسترسی آزاد۲۰۱۰Journal of Cell BiologyKangZeng, Ricardo NunesBastos, Francis A.Barr, UlrikeGruneberg

• Brca2, Pds5 and Wapl differentially control cohesin chromosome association and function

  سند علمی۲۰۱۸PLoS geneticsZiva Misulovin, Michelle Pherson, Maria Gause, Dale Dorsett

  The cohesin complex topologically encircles chromosomes and mediates sister chromatid cohesion to ensure accurate chromosome segregation upon cell division. Cohesin also participates in DNA repair and gene transcription. The Nipped-B-Mau2 protein complex loads cohesin onto chromo

• Depletion of the Chromatin Looping Proteins CTCF and Cohesin Causes Chromatin Compaction: Insight into Chromatin Folding by Polymer Modelling

  سند علمی۲۰۱۴PLoS Computational BiologyMariliis Tark-Dame, Hansjoerg Jerabek, Erik M. M. Manders, Dieter W. Heermann

  Folding of the chromosomal fibre in interphase nuclei is an important element in the regulation of gene expression. For instance, physical contacts between promoters and enhancers are a key element in cell-type-specific transcription. We know remarkably little about the principle