Coexistence of tinnitus and hyperacusis in individuals with auditory dys-synchrony: A single case study.
نویسندگان
چکیده
Certain clinical pathologies affecting the ear and hearing mechanism may co-exist. It is necessary to probe in detail into such conditions so that the pathophysiology is well understood. This research paper through a single case study tries to explain the probable pathophysiology behind coexistence of three different clinical conditions namely auditory dys-synchrony, hyperacusis and tinnitus. These conditions are common in the clinics, but the coexistence of all the three is rare and demands explanation beyond what is available in the literature. The assumed model highlights involvement of the outer hair cell's motor function in the cochlea along with the auditory central gain mechanism to explain possible pathophysiology behind coexistence of the three conditions. This model will provide insight into the probable link between the contribution of peripheral and central structures of hearing in generating tinnitus and hyperacusis in individuals having auditory dys-synchrony.
منابع مشابه
Cortical Evoked Potentials and Hearing Aids in Individuals with Auditory Dys-Synchrony.
OBJECTIVE The purpose of the present study was to investigate the relationship between cortical processing of speech and benefit from hearing aids in individuals with auditory dys-synchrony. MATERIALS AND METHODS Data were collected from 38 individuals with auditory dys-synchrony. Participants were selected based on hearing thresholds, middle ear reflexes, otoacoustic emissions, and auditory ...
متن کاملHyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans.
Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197-3208, 2014) demonstrated that efferent suppression of cochlear activity by the medial olivocochlear system is enhanced in individuals with tinnitus and/or hyperacusis. Their findings stress that atypical activity in the efferent auditory pathway may re...
متن کاملThe auditory sensitivity is increased in tinnitus ears.
Increased auditory sensitivity, also called hyperacusis, is a pervasive complaint of people with tinnitus. The high prevalence of hyperacusis in tinnitus subjects suggests that both symptoms have a common origin. It has been suggested that they may result from a maladjusted increase of central gain attributable to sensory deafferentation. More specifically, tinnitus and hyperacusis could result...
متن کاملCentral Gain Control in Tinnitus and Hyperacusis
Sensorineural hearing loss induced by noise or ototoxic drug exposure reduces the neural activity transmitted from the cochlea to the central auditory system. Despite a reduced cochlear output, neural activity from more central auditory structures is paradoxically enhanced at suprathreshold intensities. This compensatory increase in the central auditory activity in response to the loss of senso...
متن کاملNeuro Forum Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans
Sturm JJ, Weisz CJ. Hyperactivity in the medial olivocochlear efferent system is a common feature of tinnitus and hyperacusis in humans. J Neurophysiol 114: 2551–2554, 2015. First published February 18, 2015; doi:10.1152/jn.00948.2014.—Tinnitus and hyperacusis are common, burdensome sources of morbidity with a high rate of co-occurrence. Knudson et al. (J Neurophysiol 112: 3197–3208, 2014) demo...
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عنوان ژورنال:
- Intractable & rare diseases research
دوره 5 1 شماره
صفحات -
تاریخ انتشار 2016