Mapping novel traits by array-assisted bulk segregant analysis in Saccharomyces cerevisiae.
نویسندگان
چکیده
We demonstrate a new method, microarray-assisted bulk segregant analysis, for mapping traits in yeast by genotyping pooled segregants. We apply a probabilistic model to the progeny of a single cross and as little as two microarray hybridizations to reliably map an auxotrophic marker, a Mendelian trait, and a major-effect quantitative trait locus.
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عنوان ژورنال:
- Genetics
دوره 173 3 شماره
صفحات -
تاریخ انتشار 2006