MYELOID NEOPLASIA Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features
نویسندگان
چکیده
1Department of Medicine (Hematology Oncology Division), Weill Cornell Medical College, New York, NY; 2Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands; 3Department of Physiology and Biophysics and HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College, New York, NY; 4Department of Molecular Genetics, Albert Einstein College of Medicine, New York, NY; 5Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands; and Departments of 6Epidemiology and Population Health and 7Medicine, Albert Einstein College of Medicine, New York, NY
منابع مشابه
Genome-wide epigenetic analysis delineates a biologically distinct immature acute leukemia with myeloid/T-lymphoid features.
Acute myeloid leukemia is a heterogeneous disease from the molecular and biologic standpoints, and even patients with a specific gene expression profile may present clinical and molecular heterogeneity. We studied the epigenetic profiles of a cohort of patients who shared a common gene expression profile but differed in that only half of them harbored mutations of the CEBPA locus, whereas the r...
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تاریخ انتشار 2009