Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis.
نویسندگان
چکیده
A unique highly reducing polyketide synthase (HR-PKS) with a reductase domain was identified in a betaenone biosynthetic gene cluster. Successful heterologous expression and characterization of the HR-PKS and trans-acting enoyl reductase (ER) provide insights into the core structure formation with a decalin scaffold and allow reconstitution of the betaenone biosynthetic machinery.
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عنوان ژورنال:
- Chemical communications
دوره 51 10 شماره
صفحات -
تاریخ انتشار 2015