Package 'tileshuffle' Title Detection of Differentially Expressed Segments in Tiling Array Data
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چکیده
February 28, 2012 Type Package Title Detection of differentially expressed segments in tiling array data Version 0.2.0 Date 2011-04-08 Author Christian Otto, Kristin Reiche, Joerg Hackermueller Depends R (>= 2.1.0) Imports multtest, affxparser, intervals, genomeIntervals, utils, Biobase, limma Suggests Starr Maintainer Christian Otto Description This package contains functions for the analysis of tiling array data. It implements a statistical approach to detect expression or differential expression in terms of differences from the background distribution that avoids any intensity-related parameters. Moreover, it reduces the most dominant tiling array biases using an affinity-dependent permutation in conjunction with a windowing approach. License GPL-2 LazyLoad yes URL http://www.bioinf.uni-leipzig.de/Software/TileShuffle/ Collate ’TileHelper.R’ ’TileRead.R’ ’TileShuffle.R’
منابع مشابه
Detection of differentially expressed segments in tiling array data
MOTIVATION Tiling arrays have been a mainstay of unbiased genome-wide transcriptomics over the last decade. Currently available approaches to identify expressed or differentially expressed segments in tiling array data are limited in the recovery of the underlying gene structures and require several parameters that are intensity-related or partly dataset-specific. RESULTS We have developed Ti...
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تاریخ انتشار 2012