Genetic Testing for Lynch Syndrome and Other Inherited Colon Cancer Syndromes
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Professional Institutional Original Effective Date: May 13, 2011 Original Effective Date: June 13, 2011 Revision Date(s): January 1, 2012; April 10, 2012; January 15, 2013; March 26, 2013; August 21, 2013; January 1, 2015; March 18, 2015; January 1, 2016; February 3, 2016; May 25, 2016; November 9, 2016 Revision Date(s): January 1, 2012; April 10, 2012; January 15, 2013; March 26, 2013; August 21, 2013; January 1, 2015; March 18, 2015; January 1, 2016; February 3, 2016; May 25, 2016; November 9, 2016 Current Effective Date: November 9, 2016 Current Effective Date: November 9, 2016
منابع مشابه
Hereditary Nonpolyposis Colorectal Cancer (HNPCC)/Lynch Syndrome: Surveillance and Diagnostic strategies
Introduction: Hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) is an autosomal dominant genetic disease. The disease is caused by a mutation in one of four genes of the DNA mismatch repair system and increases the risk for various cancers, especially the uterine and colon cancers. The prevalence of this disease in the general population is about 1 in 500 and it causes about 2-3...
متن کاملThe genetics of hereditary colon cancer.
The genetic basis of sporadic colorectal cancer has illuminated our knowledge of human cancer genetics. This has been facilitated and catalyzed by an appreciation and deep understanding of the forms of colorectal cancer that harbor an inherited predisposition, including familial adenomatous polyposis (FAP), hereditary nonpolyposis colorectal cancer (HNPCC) or Lynch syndrome, the hamartomatous p...
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تاریخ انتشار 2016