Running Head: Atypical PKC in AICAR, Metformin and Exercise Actions

4 5 6 7 8 9 10 11 12 Sajan, M.P.*, Bandyopadhyay, G.*, Miura, A.*, Standaert, M.L.*, Nimal, S., Longnus, S.L. **, Van 13 Obberghen, E.**, Hainault, I.***, Foufelle, F.***, Kahn, R., Braun, U., Leitges, M. and Farese, 14 R.V.* ††† 15 16 17 18 19 20 21 22 23 24 25 From (a) the Research Service, James A. Haley Veterans Hospital, and Department of Internal 26 Medicine, University of South Florida College of Medicine Tampa, Fl, USA*; (b) INSERM U145, 27 Institut Federatif de Recherche 50, Faculte de Medicine, 06107 Nice Cedex 2, France**; (c) 28 INSERM U671, Centre de Recherches Biomedicales des Cordeliers, Universite Pierre et Marie 29 Curie, 75270 Paris Cedex 06, France***; (d) the Joslin Center and Harvard Medical School, 30 Boston, MA, USA, Biotechnology Centre of Oslo, Oslo, Norway; and (e) the Roskamp Institute, 31 Sarasota Fl, USA 32 33 34 35 36 Running Head: Atypical PKC in AICAR, Metformin and Exercise Actions 37 38 39 40 41 Contacting Information: Robert V. Farese, M.D. 42 James A. Haley Veterans Medical Center 43 13000 Bruce B. Downs Blvd. 44 Tampa, Fl 33612 45 Telephone, (813) 972-7662 46 Fax, (813) 972-7623 47 Email address, [email protected] 48 49 50 51 52 53 Articles in PresS. Am J Physiol Endocrinol Metab (November 3, 2009). doi:10.1152/ajpendo.00392.2009