3,4,5-Trihydroxy-N′-(1H-indol-2-ylmethylidene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)
نویسندگان
چکیده
The title compound, 2C(16)H(13)N(3)O(4)·C(18)H(14)N(4)·2CH(4)O, was crystallized from the reaction between 3,4,5-trihydroxy-benzoyl-hydrazine and indole-2-carbaldehyde in a mixture of ethanol and methanol. The compound is a stoichiometric 2:1 cocrystal of the methanol-solvated reaction product, 3,4,5-trihydr-oxy-N'-(1H-indol-2-ylmethyl-idene)benzohydrazide and 1H-indole-2-carbaldehyde azine that arose unexpectedly during the synthesis. The former mol-ecules are linked by O-H⋯O hydrogen bonds and also by π-π stacking inter-actions between benzoyl-hydrazide rings into a two-dimensional network. The methanol solvent mol-ecules are hydrogen bonded to this network. The centrosymmetric azine mol-ecules are not engaged in hydrogen bonding.
منابع مشابه
3,4,5-Trihydroxy-N′-[(1-methyl-1H-indol-2-yl)methylidene]benzohydrazide
The structure of the title compound, C(17)H(15)N(3)O(4), displays inter-molecular O-H⋯N and O-H⋯O hydrogen bonding between adjacent mol-ecules. Intra-molecular O-H⋯O hydrogen bonds also occur. The molecule is essentially planar with a deviation of 0.090 (1) Å from the best plane running through the connected ring systems.
متن کامل3,4,5-Trihydroxy-N′-(1H-indol-3-ylmethylidene)benzohydrazide pentahydrate
The two aromatic parts of the title compound, C(16)H(13)N(3)O(4)·5H(2)O, are connected through a conjugated -CH=N-NH-C(O)- fragment, giving an almost planar mol-ecule. The organic mol-ecules and uncoordinated water mol-ecules are linked by N-H⋯O and O-H⋯O hydrogen bonds into a three-dimensional network.
متن کامل1H-Indole-3-carbaldehyde azine
The molecule of the title compound, C(18)H(14)N(4), lies on a center of inversion such that there is one half-mol-ecule in the asymmetric unit. The N-N single bond adopts a trans configuration and the indole fused-ring system is nearly coplanar with the -CH=N-N=CH- fragment [dihedral angle = 9.8 (2)°]. Adjacent mol-ecules are linked by indole-azine N-H⋯N hydrogen bonds into a layer motif.
متن کامل(Z)-3-(1H-Indol-3-yl)-2-(3-thienyl)acrylonitrile and (Z)-3-[1-(4-tert-butylbenzyl)-1H-indol-3-yl]-2-(3-thienyl)acrylonitrile.
(Z)-3-(1H-Indol-3-yl)-2-(3-thienyl)acrylonitrile, C15H10N2S, (I), and (Z)-3-[1-(4-tert-butylbenzyl)-1H-indol-3-yl]-2-(3-thienyl)acrylonitrile, C26H24N2S, (II), were prepared by base-catalyzed reactions of the corresponding indole-3-carboxaldehyde with thiophene-3-acetonitrile. 1H/13C NMR spectral data and X-ray crystal structures of compounds (I) and (II) are presented. The olefinic bond connec...
متن کاملSynthesis Characterization and Biological Evaluation of Novel Thiazole Derivatives Containing Indole Moiety Bearing-Tetrazole
Purpose: The article is aimed to synthesize,characterize and screening the biological activity of a series of Synthesis of 1-(2-(3-(3-chloro-1-(4-substituted phenyl)-4-tetrazole-2-yl)-1H-indol-1-yl)acetyl)-4-(2-(4substituted phenyl)hydrazono)-3-(trifluoromethyl)-1H-pyrazol-5(4H)-one 4(a-f). Indole-3-carbaldehyde and chloro ethyl acetate were dissolved in DMF. To this reaction mixture anhydrous ...
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عنوان ژورنال:
دوره 66 شماره
صفحات -
تاریخ انتشار 2009