Lymphoma presenting as secondary HLH: a review with a tale of two cases.

Lymphoma-associated hemophagocytic syndrome is a disease with an extremely poor prognosis and can be easily missed at diagnosis. Identifying and treating the underlying lymphoma early is of utmost importance because that directly affects outcome. Thorough and repeated testing for the underlying cause is imperative. Further studies are necessary to better understand the most appropriate front-line therapy. Allogeneic bone marrow transplant has shown promising results in children and needs to be studied further in adults.