Synthesis of allyl selenides by palladium-catalyzed decarboxylative coupling.
نویسندگان
چکیده
This communication details the Pd-catalyzed decarboxylation of selenocarbonates; use of a chiral nonracemic catalyst affords enantioenriched allyl selenides which undergo stereospecific [2,3]-sigmatropic rearrangements to form enantioenriched allylic amines and chlorides.
منابع مشابه
Palladium-catalyzed decarboxylative cross-coupling of alkynyl carboxylic acids with arylboronic acids.
A highly efficient and mild palladium-catalyzed decarboxylative cross-coupling of aryl boronic acids and alkynyl carboxylic acids for the synthesis of unsymmetrical substituted alkynes is described for the first time.
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Herein, we describe a study into the scope and origin of an enantiodivergent effect in the palladium-catalyzed decarboxylative asymmetric protonation. By switching the achiral proton source, both enantiomers of a series of tertiary α-aryl-1-indanones are readily accessed from the corresponding α-aryl-β-keto allyl esters. In this example of dual stereocontrol, enantioselectivities up to 94% (S) ...
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عنوان ژورنال:
- Chemical communications
دوره 28 شماره
صفحات -
تاریخ انتشار 2008